Maria Manuela Gaspar

Principal Investigator
Short bio & current area(s) of interest
Maria Manuela de Jesus Guilherme Gaspar is a Researcher at the Faculty of Pharmacy, Universidade de Lisboa and member of the Research Institute for Medicines, iMed.ULisboa since January 2009. The research has been focused on design, development and biological evaluation of drug delivery systems for improving the therapeutic index of incorporated molecules for the treatment of infectious, inflammatory and cancer diseases. Design and characterization of appropriated delivery systems, of lipid and polymeric nature, for different routes of administration namely pulmonary, intranasal and parenteral. In vitro and in vivo evaluation of low and high molecular weight molecules namely antibiotics (rifabutin, paramomycin) and enzymes (L-Asparaginase , Superoxide Dismutaser). In vitro and in vivo screening of new synthesized molecules and metal-based complexes with antitumor activity. Establishment of infectious and cancer murine models, such as M. avium, M. tuberculosis, leishmania, MRSA, melanoma, colon cancer, for evaluating the therapeutic effect of developed nanoformulations. She has participated in more than 30 research projects as team member or as PI. She has been supervising PhD, master and undergraduate students. She is co-author of more than 65 articles in journals (Indexed Scopus), book chapters (6) and patents. She is responsible for the animal facilities and member of the welfare organ of the Faculty of Pharmacy since 2011. In addition, she also belongs to governing bodies of the Portuguese Society for Laboratory Animal Science.

BSc (1983) in Instituto Superior de Engenharia de Lisboa, Lisbon, Portugal

MSc (1992) in Instituto Superior de Engenharia de Lisboa, Lisbon, Portugal

PhD (2005) in Pharmaceutical Technology, University of Lisbon, Lisbon, Portugal

Postdoctoral Fellow, Trinity College, University of Dublin, Dublin, Ireland

Principal Investigator, iMed.ULisboa, Faculty of Pharmacy, University of Lisbon, Lisbon, Portugal

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Faculdade de Farmácia da Universidade de Lisboa | Av. Professor Gama Pinto
1649-003 Lisboa | Portugal

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