Patricia-Serra

Patricia Serra

Researcher
Short bio & current area(s) of interest
Patrícia completed her PhD at Research Institute for Medicines (iMed.ULisboa) working on the discovery of multiple new hit compounds that can be used as useful starting points to initiate hit-to-lead programs towards drug candidates for HIV-1 and HIV-2 therapy, using computational techniques. She holds a bachelor degree in Chemistry and a master degree in Chemistry specialized in Chemistry, Health and Nutrition from University of Lisboa Faculty of Sciences. She works on the development and optimization of a computer-assisted drug design approach of an important HIV-2 glycoprotein that allows us to explore and gain further insights at the molecular level into protein structures and interactions crucial for HIV-2 inhibition. A 3D structure of HIV-2ROD gp125 was generated by a homology modelling campaign and these findings reveal important aspects of the structural characterization of the glycoproteins fundamental to the viral entry mechanism of HIV. HIV, viral glycoprotein, homology modelling, molecular dynamics, structural elucidation, structure-function relationship

BSc (2011) in Chemistry, University of Lisboa Faculty of Sciences, Lisboa, Portugal

MSc (2012) in Chemistry, University of Lisboa Faculty of Sciences, Lisboa, Portugal

PhD (2021) in Pharmacy, specialty of Pharmaceutical and Therapeutic Chemistry, University of Lisboa Faculty of Pharmacy, Lisboa, Portugal

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Faculdade de Farmácia da Universidade de Lisboa | Av. Professor Gama Pinto
1649-003 Lisboa | Portugal


Phone | +351 217 946 400
Fax | +351 217 946 470
Web | www.imed.ulisboa.pt
Email | imed.ulisboa@ff.ulisboa.pt

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