H2020 Societal Challenges – Health, demographic change and well-being
MADGIC
MADGIC proposes to generate human cellular models allowing for the purification of neural cell types involved in AD, which will be used to generate novel readouts. Patient neural cells generated by reprogramming technologies allow access to homogenous cultures, which grown alone or in mixed 3D cultures will be used to address disease relevant phenotypes both in vitro, and in vivo after transplantation into mouse models.
| Funding | ERA-NET-Cofund Transnational: Neurodegenerative Disease Research 2015 |
| Call/Topic | ERA-NET: Establishing synergies between the Joint Programming on Neurodegenerative Diseases Research and Horizon 2020 |
| Title | MADGIC: Generation of Improved cellular and animal models for identification of disease phenotype and new therapeutic targets of Alzheimer’s Disease |
| Start date | January 2016 |
| Duration | 36 months |
| Project coordinator | Jari Koistinaho, University of Eastern Finland, Finland |
| Project Partners | Laurent Roybon, University of Lund, Sweden Gunnar Gouras, University of Lund, Sweden Claire Rampon, University of Toulouse, France Dora Brites, iMed.ULisboa, Faculty of Pharmacy, University of Lisbon, Portugal Michael T. Heneka, University Hospital of Bonn, Germany Frank Edenhofer, University of Wurzburg, Germany Tarja Malm, University of Eastern Finland, Finland |