Maria H. L. Ribeiro

PhD (1994) in Pharmacy (Pharmaceutical Chemistry), Universidade de Lisboa
Associate Professor, Pharmaceutical Chemistry and Therapeutics, Faculdade de Farmácia, Universidade de Lisboa
Group Leader, Chemical Biology and Toxicology at iMed.ULisboa

Faculdade de Farmácia, Universidade de Lisboa — Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal

T (+351) 217 946 400
F (+351) 217 946 470
Researcher ID A-5993-2008
Group Researcher ID B-4215-2014
Scopus Author ID 7201715065

Research Interests

Maria H Ribeiro leads investigation in the Biotechnology and Bioengineering area, on the design, development and characterization of new (bio)materials and biotech compounds (e.g. small-molecules and proteins) towards therapeutics (against infectious, cancer and neurodegenerative disease) and functional foods.

Her focus is based on rational strategies of (i) enzyme and cell-based culture systems with process intensification through miniaturization to bioseparations; ii) biocatalysts performance improvement (e.g. immobilization); iii) tailoring (bio)responsive polymeric biomaterials networks; iv) innovative bioconversions, as glycosides, glycolipids and lipoamino acids production, to be used as bioactive compounds, delivery and transfection agents

Selected Publications

Martins S, Nunes M, Ribeiro MHL. Exploring magnetic and imprinted cross-linked enzyme aggregates of rhamnopyranosidase in microbioreactors. Bioresource Technol 2018; 249: 704-712.

Míguez N, Gimeno-Pérez M, Fernández-Polo D, Cervantes FV, Ballesteros AO, Fernández-Lobato M, Ribeiro MHL, Plou FJ. Immobilization of the β-fructofuranosidase from Xanthophyllomyces dendrorhous by entrapment in polyvinyl alcohol and its application to neo-fructooligosaccharides production. Catalysts 2018; 8: 201, 1-12.

Nunes MAP, Martins S, Rosa ME, Gois PMP, Fernandes PCB, Ribeiro MHL. Improved thermostable polyvinyl alcohol electrospun nanofibers with entangled naringinase used in a novel mini-packed bed reactor. Bioresource Technol 2016; 213: 208–215

Ribeiro IAC, Faustino CMC, Guerreiro PS, Frade RFM, Bronze MR, Castro MF, Ribeiro MHL. Development of novel sophorolipids with improved cytotoxic activity towards MDA-MB-231 breast cancer cells. J Mol Recogn 2015; 28: 155-65.

Nunes MAP, Rosa ME, Fernandes PCB, Ribeiro MHL. Operational stability of naringinase PVA lens-shaped microparticles in batch stirred reactors and mini packed bed reactors-one step closer to industry. Bioresource Technol 2014; 164: 362–370.