João A. Lopes

PhD (2001) in Chemical Engineering, Instituto Superior Técnico, Universidade técnica de Lisboa

Assistant Professor, Galenic Pharmacy and Pharmaceutical Technology, Faculdade de Farmácia, Universidade de Lisboa


Faculdade de Farmácia, Universidade de Lisboa — Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal

T (+351) 217 946 400
F (+351) 217946470
Researcher ID H-1733-2011
Group Researcher ID B-4826-2014
Scopus Author ID 7202733600

Research Interests

João Lopes current research interests are focused on the mathematical modelling aspects of solid dosage forms and nanoparticulate systems for modified drug delivery including manufacturing aspects focused on process analytical technology methodologies and incorporating concepts as QbD. He founded and coordinates since 2008 the research unit “Chemometrics and Process Analytical Technology” located at the FFUP. Multiple PAT-based systems for fast assessment of quality attributes of different products have been developed in partnership with industrial companies.

Selected Publications

Silva Filho SF, Pereira AC, Sarraguça JMG, Sarraguça MC, Lopes JA, Façanha Filho PF, dos Santos AO, Ribeiro PR. Synthesis of a glibenclamide cocrystal: full spectroscopic and thermal characterization. J Pharm Sci 2018; 107:1597-1604

Machado Jr JC, Faria MA, Ferreira IMPLVO, Páscoa RNMJ, Lopes JA. Varietal discrimination of hop pellets by near and mid infrared spectroscopy. Talanta 2018; 180:69-75

Silva AFT, Sarraguça MC, Ribeiro PR, de Beer T, Lopes JA. Statistical process control of cocrystallization processes: A comparison between OPLS and PLS. Int J Pharm 2017; 520:29-38

Silva AF, Sarraguça MC, Fonteyne M, Vercruysse J, de Leersnyder F, Vanhoorne V, Bostijn N, Verstraeten M, Vervaet C, Remon JP, de Beer T, Lopes JA. Multivariate statistical process control of a continuous pharmaceutical twin-screw granulation and fluid bed drying process. Int J Pharm 2017; 528:242-252

Brereton RG, Jansen J, Lopes JA, Marini F, Pomerantsev A, Rodionova O, Roger JM, Walczak B, Tauler R. Chemometrics in analytical chemistry-part I: history, experimental design and data analysis tools. Anal Bioanal Chem 2017; 409:5891-5899