Helder Mota-Filipe

PhD (1996) in Pharmacy (Pharmacology), Universidade de Lisboa
Associate Professor, Social Pharmacy, Faculdade de Farmácia, Universidade de Lisboa
Executive Member of the National Ethics Committee for Clinical Research

Faculdade de Farmácia, Universidade de Lisboa — Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal

T (+351) 217 987 117
F (+351) 217 946 470
Researcher ID M-6298-2013
Group Researcher ID B-5723-2014
Scopus Author ID 6604005426

Research Interests

Mota-Filipe performs research on novel innovative therapeutic approaches for human diseases in the areas of shock, sepsis and inflammation. Areas of research include neuroprotection for transient focal cerebral ischemia, new targets for the modulation of acute lung injury, inflammatory bowel disease or pharmacological interventions on ischemia-reperfusion injury and dysfunction. Mota-Filipe is also interested on the application of its research in early stages of drug discovery programs. More recently, Mota-Filipeis also interested on the study of health policy measures and its contribution for a more cost-effective use of medicines and other health technologies.


Selected Publications

Mateus V, Rocha J, Alves P, Mota-Filipe H, Sepodes B, Pinto R. Thiadiazolidinone-8 Ameliorates Inflammation Associated with Experimental Colitis in Mice. Pharmacology 2018; 101: 35-42.

Moorkens E, Vulto AG, Huys I, Dylst P, Godman B, Keuerleber S, Claus B, Dimitrova M, Petrova G, Sović-Brkičić L, Slabý J, Šebesta R, Laius O, Karr A, Beck M, Martikainen JE, Selke GW, Spillane S, McCullagh L, Trifirò G, Vella Bonanno P, Mack A, Fogele A, Viksna A, Władysiuk M, Mota-Filipe H, Meshkov D, Kalaba M, Mencej Bedrač S, Fürst J, Zara C, Skiöld P, Magnússon E, Simoens S. Policies for biosimilar uptake in Europe: An overview. PLoS One 2017; 12: e0190147.

de Jesus Gaffney V, Mota-Filipe H, Pinto RA, Thiemermann C, Loureiro M, Cardoso VV, Benoliel MJ, Almeida CM. Chemical and biochemical characterization and in vivo safety evaluation of pharmaceuticals in drinking water. Environ Toxicol Chem 2016; 35: 2674-2682.

Mateus V, Rocha J, Alves P, Mota-Filipe H, Sepodes B, Pinto RM. Anti-Inflammatory Effect of Erythropoietin in the TNBS-induced Colitis. Basic Clin Pharmacol Toxicol 2017; 120: 138-145.

Sousa-Martins D, Caseli L, Figueiredo MC, Sa E Cunha C, Mota-Filipe H, Souza-Lima A, Belfort R Jr, Rodrigues E, Maia M. Comparing the mode of action of intraocular lutein-based dyes with synthetic dyes. Invest Ophthalmol Vis Sci 2015; 56: 1993-2000.