Bruno L. Victor
PhD (2007) in Biochemistry, ITQB – Universidade Nova de Lisboa
Post-Doctoral Fellow, iMed.ULisboa, Faculdade de Farmácia, Universidade de Lisboa
Faculdade de Farmácia, Universidade de Lisboa — Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal
Research Interests
Bruno L. Victor focused his research career on the use of different computational methodologies to different drug discovery projects in industry and academia. Currently he his working under the supervision of Rita Guedes, at the Computational Medicinal Chemistry Laboratory at iMed, where he is developing an innovative drug discovery workflow applied to the development of new promising lead candidates for cancer treatment.
Selected Publications
Vila-Viçosa D, Victor BL, Ramos J, Machado D, Viveiros M, Switala J, Loewen PC, Leitao R, Martins F, Machuqueiro M. Insights on the Mechanism of Action of INH-C10 as an Antitubercular Prodrug. Molec Pharmac 2017; 14:4597-4605.
Machuqueiro M, Victor BL, Switala J, Villanueva J, Rovira C, Fita I, Loewen PC. The Catalase Activity of Catalase-Peroxidases Is Modulated by Changes in the pKa of the Distal Histidine. Biochemistry 2017; 56: 2271-2281.
Victor BL, Lousa D, Antunes JM, Soares CM. Self-assembly molecular dynamics simulations shed light into the interaction of the influenza fusion peptide with a membrane bilayer. J Chem Inf Model 2015; 55: 795-805.
Damas JM, Filipe LCS, Campos SRR, Lousa D, Victor BL, Baptista AM, Soares CM. Predicting the thermodynamics and kinetics of helix formation in a cyclic peptide model. J Chem Theo Comp 2013; 9: 5148-5157.
Victor BL, Baptista AM, Soares CM. Structural determinants for the membrane insertion of the transmembrane peptide of hemagglutinin from influenza virus. J Chem Inf Model 2012; 52: 3001-3012.