March 2017

First tuberculosis molecular epidemiological survey in Angola led by iMed.ULisboa researchers

The results of the first tuberculosis (TB) molecular epidemiological survey in Angola have recently been released. This study, now published in Scientific Reports (Nature Publishing Group), led by iMed.ULisboa  and in collaboration with the Global Health and Tropical Medicine (GHTM) from Instituto de Higiene e Medicina Tropical (IHMT), Centro de Investigação Interdisciplinar Egas Moniz (CiiEM) from Instituto Superior de Ciências da Saúde Egas Moniz (ISCSEM) and Hospital da Divina Providência, in Luanda, is the first to characterize the genetic profile of Mycobacterium tuberculosis strains circulating in Luanda.

The genotypic characterization of these strains has defined the main M. tuberculosis circulating clones, and its associated recent transmission events and geographical dispersion, thus generating a much deeper knowledge of what is the TB transmission dynamics in Luanda.

The study was led by the Molecular Mycobacteriology Laboratory (Principal Investigator Isabel Portugal) of the Molecular Microbiology and Biotechnology Group in collaboration with the HIV Evolution, Epidemiology and Prevention Group (Principal Investigator Nuno Taveira).