PhD (2004) in Pharmacy (Pharmacognosy), University of Lisbon
Associate Professor, Pharmacological Sciences, Faculdade de Farmácia, Universidade de Lisboa
Faculdade de Farmácia, Universidade de Lisboa — Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal
Silva work is devoted to the quality, safety, mode of action and regulatory issues of the CPLP traditional herbal medicines. Approaches used include metabolomic studies concerning target marker compounds and in vivo and in vitro tools: animal models of diabetes and in vitro screen of mechanistic actions involved in antidiabetic properties, like alfa and beta-glucosidase inhibition; anti-inflammatory activity; in vitro screen of antimicrobial activity against different microorganisms and of antitumor activity against different human cell lines.
Malmir M, Serrano R, Caniça M, Silva-Lima B, Silva O. A Comprehensive Review on the Medicinal Plants from the Genus Asphodelus. Plants 2018; 7: 20.
Alexandre-Pires A, Martins C, Galvão AM, Miranda M, Silva O, Ligeiro D, Nunes T. Understanding the inguinal sinus in sheep (Ovis aries)—Morphology, secretion, and expression of progesterone, estrogens, and prolactin receptors. Int J Mol Sci 2017; 18 pii: E1516.
Ramalhete N, Machado A, Serrano R, Gomes ET, Mota-Filipe H, Silva O. Comparative study on the in vivo antidepressant activities of the Portuguese Hypericum foliosum, Hypericum androsaemum and Hypericum perforatum medicinal plants. Industrial Crops and Products 2016; 82: 29-36.
Encarnação S, de Mello-Sampayo C, Graça NAG, Catarino L, da Silva IBM, Lima BS, Silva O. Total phenolic content, antioxidant activity and pre-clinical safety evaluation of an Anacardium occidentale stem bark Portuguese hypoglycemic traditional herbal preparation. Industrial Crops and Products 2016; 82: 171-178.
Malmir M, Gohari AR, Saeidnia S, Silva O. A new bioactive monoterpene-flavonoid from Satureja khuzistanica. Fitoterapia 2015; 105: 107-112.