Nuno G. Oliveira

PhD (2003) in Pharmacy (Toxicology), Universidade de Lisboa

MSc (1998) in Food Quality Control and Toxicology, Faculdade de Farmácia, Universidade de Lisboa

Degree in Pharmaceutical Sciences (1993), FFULisboa

Assistant Professor with Aggregation (Toxicology) at FFULisboa

Faculdade de Farmácia, Universidade de Lisboa — Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal

T (+351) 217 946 400
F (+351) 217 946 470
Researcher ID A-7407-2014
Group Researcher ID B-4215-2014
Scopus Author ID 7005130391

Research Interests

Nuno G. Oliveira has been interested in different areas of Toxicology, particularly in Genetic Toxicology. He has been studying the mechanisms of DNA damage and repair induced by chemotherapeutic drugs, food mutagens, ionizing radiation and radiomimetic compounds. Currently, he is involved in the study of in vitro approaches towards breast and renal cancer therapy using superoxide dismutase mimics (SODm) and DNA repair inhibitors.

Selected Publications

Costa JG, Saraiva N, Guerreiro PS, Louro H, Silva MJ, Miranda JP, Castro M, Batinic-Haberle I, Fernandes AS, Oliveira NG. Ochratoxin A-induced cytotoxicity, genotoxicity and reactive oxygen species in kidney cells: An integrative approach of complementary endpoints. Food Chem Toxicol 2016; 87: 65–76.

Guerreiro PS, Corvacho E, Costa JG, Saraiva N, Fernandes AS, Castro M, Miranda JP, Oliveira NG. The APE1 redox inhibitor E3330 reduces collective cell migration of human breast cancer cells and decreases chemoinvasion and colony formation when combined with docetaxel. Chem Biol Drug Des 2017. doi: 10.1111/cbdd.12979.

Fernandes AS, Saraiva N, Oliveira NG. Redox therapeutics in breast cancer: role of SOD mimics, in Redox-active therapeutics (Rebouças JS, Batinic-Haberle I, Spasajevic I, Warner DS, Clair D, eds). Springer-Verlag, US. 2016; Chapter 18, pp. 451-467.

Ramos DL, Gaspar JF, Pingarilho M, Gil OM, Fernandes AS, Rueff J, Oliveira NG. Genotoxic effects of doxorubicin in cultured human lymphocytes with different glutathione S-transferase genotypes. Mutat Res 2011; 724: 28–34.

Martins C*, Oliveira NG*, Pingarilho M, Gamboa da Costa G, Martins V, Marques MM, Beland FA, Churchwell MI, Doerge DR, Rueff J, Gaspar, JF. Cytogenetic damage induced by acrylamide and glycidamide in mammalian cells: correlation with specific glycidamide-DNA adducts. Toxicol Sci. 2007; 95: 383–390.