Maria João Gracias Fernandes da Costa Catalão

PhD (2010) in Pharmacy (Microbiology), Universidade de Lisboa

Posdoctoral research at ITQB NOVA, Universidade Nova de Lisboa

Assistant Researcher (FCT Investigator 2015), Faculdade de Farmácia, Universidade de Lisboa

Faculdade de Farmácia, Universidade de Lisboa — Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal

T (+351) 217 946 400
F (+351) 217 946 470
Researcher ID B-6731-2017
Group Researcher ID B-4239-2014
Scopus Author ID 24447855200

Research Interests

Maria João research aims to understand: i) how the atypical structure/modifications of the mycobacterial cell wall modulate its interaction with the immune system and contribute to high levels of antibiotic resistance; ii) if the mycobacterial peptidoglycan is concealed from the infected host by structures exposed on the cell surface; iii) if the adaptation of mycobacterial peptidoglycan synthesis during dormancy prevents recognition by the immune system and increases drug resistance.

Selected Publications

Catalão MJ, Figueiredo J, Henriques MX, Gomes JP, Filipe SR. Optimization of fluorescent tools for cell biology studies in Gram-positive bacteria. PLoS One 2014; 9:e113796.

Atilano ML, Pereira PM, Vaz F, Catalão MJ, Reed P, Grilo IR, Sobral RG, Ligoxygakis P, Pinho MG, Filipe SR. Bacterial autolysins trim cell surface peptidoglycan to prevent detection by the Drosophila innate immune system. Elife 2014; 3:e02277.

Henriques MX*, Catalão MJ*, Figueiredo J, Gomes JP, Filipe SR. Construction of improved tools for protein localization studies in Streptococcus pneumoniae. PLoS One 2013; 8:e55049. *Joint first authors.

Catalão MJ, Gil F, Moniz-Pereira J, São-José C, Pimentel M. Diversity in bacterial lysis systems: bacteriophages show the way. FEMS Microbiology Reviews 2013; 37:554-571.

Catalão MJ, Gil F, Moniz-Pereira J, Pimentel M. The mycobacteriophage Ms6 encodes a chaperone-like protein involved in the endolysin delivery to the peptidoglycan. Mol Microbiology 2010; 77:672-686.