Maria Bárbara F. Martins

PhD in Biotechnology, Instituto Superior Técnico, Universidade Técnica de Lisboa

Principal Researcher, Departamento de Farmácia Galénica e Tecnologia Farmacêutica

Faculdade de Farmácia, Universidade de Lisboa

Faculdade de Farmácia, Universidade de Lisboa — Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal

Researcher ID I-2047-2012
Group Researcher ID B-4826-2014
Scopus Author ID 36922284600

Research Interests

Barbara has more than 30 years of experience on design of carriers for therapeutic and analytical purposes.  Performed lab work, oriented graduation students, leaded and participated in projects. Main areas of work are the optimization of colloidal carriers for therapeutic biomolecules, conjugation of enzymes do the surface of nanoparticles. More recently their studies involve the design of hybrid nanostructures for different purposes, among them for diagnostic imaging, MRI. Some of the  work led to patentable inventions.

Selected Publications

Matos JC, Avelar I, Martins MBF, Gonçalves MC. Greensilica Vectors for smart textiles. Carbohydrate polymers 2017; 156: 268-275.

Corvo ML, Marinho HS, Marcelino P, Lopes R, Vale CA, Marques CR, Martins LCD, Laverman P, Storm G, Martins MBF. Superoxide Dismutase Enzymosomes: Carrier Capacity Optimization, in Vivo Behaviour and Therapeutic Activity. Pharmaceutical Research 2015; 32: 91-102.

Gonçalves MC, Fortes LM, Martins MBF, Carvalho A, Feio G. Multifuntional superparamagnetic nanosystem as contrast agent for magnetic resonance imaging and its production method. World Intellectual Property Organization. 2015 Patent: WO2015026252.

Martins MBF, Corvo ML, Marcelino P, Marinho HS, Feio G, Carvalho A. New long circulating magnetoliposomes as contrast agents for detection of ischemia-reperfusion injuries by MRI. Nanomedicine: Nanotechnology, Biology and Medicine 2014; 10: 207-214.

Martins MBF, Gonçalves APV, Cruz MEM. Biochemical characterization of a bioconjugate of L-asparaginase. Bioconjugate Chemistry 1996; 7: 430-435.