Luís Filipe Pleno de Gouveia

PhD (2003) in Pharmacy (Pharmaceutics), Universidade de Lisboa
Assistant Professor, Pharmaceutics

Faculdade de Farmácia, Universidade de Lisboa — Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal

T (+351) 217 946 400
F (+351) 217 946 470
Researcher ID J-7208-2012
Group Researcher ID B-4831-2014
Scopus Author ID 25646145600

Research Interests

Gouveia current research interests range from medicines development (nanoparticulate systems and others) to in-silico modeling and simulation of physiological and pharmacokinetic systems and phenomena. Other areas of work include advanced data analysis, chemometrics, experimental design and Quality by design based drug products development.

Selected Publications

Tukulula M, Gouveia L, Paixao P, Hayeshi R, Naicker B, Dube A; Functionalization of PLGA Nanoparticles with 1, 3-β-glucan Enhances the Intracellular Pharmacokinetics of Rifampicin in Macrophages. Pharmaceutical research 2018; 35: 111

Paixão P, Gouveia LF, Silva N, Morais JAG. Evaluation of dissolution profile similarity–Comparison between the f2, the multivariate statistical distance and the f2 bootstrapping methods. European Journal of Pharmaceutics and Biopharmaceutics 2017; 112: 67-74

Marto J, Gouveia LF, Gonçalves LM, Gaspar DP, Pinto P, Carvalho FA. A quality by design (QbD) approach on starch-based nanocapsules: a promising platform for topical drug delivery. Colloids and Surfaces B: Biointerfaces 2016; 143: 177-185

Gener P, Gouveia LP, Sabat GR, de Sousa Rafael DF, Fort NB, Arranja A, Fernández y, Miñana Prietoa R, Sayos Ortega J, Arango D, Abasolo I, Videira M, Schwartz Jr S . Fluorescent CSC models evidence that targeted nanomedicines improve treatment sensitivity of breast and colon cancer stem cells. Nanomedicine: nanotechnology, biology, and medicine 2015; 11: 1883-1892.

Videira MA, Arranja AG, Gouveia LF. Experimental design towards an optimal lipid nanosystem: a new opportunity for paclitaxel-based therapeutics. European Journal of Pharmaceutical Sciences 2013; 49: 302-310.