Luís Filipe Pleno de Gouveia
PhD (2003) in Pharmacy (Pharmaceutics), Universidade de Lisboa
Assistant Professor, Pharmaceutics
Faculdade de Farmácia, Universidade de Lisboa — Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal
Gouveia current research interests range from medicines development (nanoparticulate systems and others) to in-silico modeling and simulation of physiological and pharmacokinetic systems and phenomena. Other areas of work include advanced data analysis, chemometrics, experimental design and Quality by design based drug products development.
Tukulula M, Gouveia L, Paixao P, Hayeshi R, Naicker B, Dube A; Functionalization of PLGA Nanoparticles with 1, 3-β-glucan Enhances the Intracellular Pharmacokinetics of Rifampicin in Macrophages. Pharmaceutical research 2018; 35: 111
Paixão P, Gouveia LF, Silva N, Morais JAG. Evaluation of dissolution profile similarity–Comparison between the f2, the multivariate statistical distance and the f2 bootstrapping methods. European Journal of Pharmaceutics and Biopharmaceutics 2017; 112: 67-74
Marto J, Gouveia LF, Gonçalves LM, Gaspar DP, Pinto P, Carvalho FA. A quality by design (QbD) approach on starch-based nanocapsules: a promising platform for topical drug delivery. Colloids and Surfaces B: Biointerfaces 2016; 143: 177-185
Gener P, Gouveia LP, Sabat GR, de Sousa Rafael DF, Fort NB, Arranja A, Fernández y, Miñana Prietoa R, Sayos Ortega J, Arango D, Abasolo I, Videira M, Schwartz Jr S . Fluorescent CSC models evidence that targeted nanomedicines improve treatment sensitivity of breast and colon cancer stem cells. Nanomedicine: nanotechnology, biology, and medicine 2015; 11: 1883-1892.
Videira MA, Arranja AG, Gouveia LF. Experimental design towards an optimal lipid nanosystem: a new opportunity for paclitaxel-based therapeutics. European Journal of Pharmaceutical Sciences 2013; 49: 302-310.