José Moniz-Pereira

PhD (1983) in Pharmacy (Microbiology), Universidade de Lisboa
Full Professor, Microbiology and Immunology

Faculdade de Farmácia, Universidade de Lisboa — Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal

T (+351) 217 946 430
F (+351) 217 946 470
Group Researcher ID B-5277-2014
Scopus Author ID 6603437879

Research Interests

We are interested to elucidate some aspects of: mycobacterial cell wall biogenesis; Mycobacteria interactions with cells; and biology of Mycobacterial latency.
Another area of interest is Human immunodeficiency virus (HIV), specially, HIV2. Our group seeks to answer to the fundamental question:” Why is HIV2 less virulent than HIV-1? We are looking for cellular factors essential to the life cycle of HIV that might, in the future, constitute new targets for therapeutic interventions.

Selected Publications

Catalão MJ, Gil F, Moniz-Pereira J, Pimentel M.  2011. Functional analysis of the holin-like proteins of mycobacteriophage Ms6. Journal of Bacteriology 193:2793–2803.

Catalão MJ, Gil F, Moniz-Pereira J, Pimentel M. 2010. The mycobacteriophage Ms6 encodes a chaperone-like protein involved in the endolysin delivery to the peptidoglycan. MolecularMicrobiology 77:672–686.

N, Moita LF, Goncalves J. 2010. Novel HIV-1 Knockdown Targets Identified by an Enriched Kinases/Phosphatases shRNA Library Using a Long-Term Iterative Screen in Jurkat T-Cells. PLoS ONE 5:e9276doi:10.1016/j.virusres.2009.01.012.

Anes, E., Kühnel, M. P., Bos, E., Moniz-Pereira, J., Habermann, A., & Griffiths, G. (2003). Selected lipids activate phagosome actin assembly and maturation resulting in killing of pathogenic mycobacteria. Nature Cell Biology, 5(9), 793–802. doi:10.1038/ncb1036.

Azevedo-Pereira, J. M., Santos-Costa, Q., Mansinho, K., & Moniz-Pereira, J. (2003). Identification and characterization of HIV-2 strains obtained from asymptomatic patients that do not use CCR5 or CXCR4 coreceptors Virology, 313(1), 136–146. doi:10.1016/S0042-6822(03)00343-X.