José A. G. Morais

PhD (1980) in Pharmaceutical Chemistry, University of Michigan, Ann Arbor, MI, USA
Full Professor, Pharmacological Sciences, Faculdade de Farmácia, Universidade de Lisboa

Faculdade de Farmácia, Universidade de Lisboa — Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal

T (+351) 2179 46 431
F (+351) 217 946 470
Researcher ID E-6322-2014
Group Researcher ID B-5723-2014
Scopus Author ID 7102340168

Research Interests

His scientific areas of research interest are varied and include Absorption Pharmacokinetics: Bioavailability/ Bioequivalence; Therapeutic Drug Monitoring (TDM), Population Pharmacokinetics, Basic Pharmacokinetics, including modelling and simulation, Medicines Quality Control, Bioanalytical Methodology and Pharmaceutical Technology, especially Novel Drug Delivery Systems. He has been invited speaker in ca. 120 conferences and 150 communications in scientific meetings, co-authored more than 60 scientific articles, participated in the organisation of  ca. 60 scientific meetings and supervised 11 Master and 17 PhD theses. He’s focusing now on in silico prediction of pharmacokinetic characteristics, and in vitro models of drug absorption

Selected Publications

Estudante M, Morais JAG, Soveral G, Benet LZ. Intestinal drug transporters: An overview. Adv Drug Deliv Rev 2013; 65:1340-56

Paixão P, Gouveia LF, Morais JAG. An alternative single dose parameter to avoid the need for steady-state studies on oral extended-release drug products. Eur J Pharm Biopharm 2012; 80: 410-7; (Outstanding Manuscript Award by the American Association of Pharmaceutical Scientists, Chicago, 13 October, 2012).

Carvalheiro M, Jorge J, Eleutério C,Pinhal AF, Sousa AC, Morais JAG, Cruz ME. Trifluralin liposomal formulations active against Leishmania donovani infections. Eur J Pharm Biopharm 2009; 71: 292–6.

Moreira A, Lobato R, Morais J, Silva S, Ribeiro J, Figueira A, Fernandes A, Oliveira J, Passos-Coelho JL. Influence of the Interval Between the Administration of Doxorubicin and Paclitaxel on the Pharmacokinetics of these Drugs in Patients with Locally Advanced Breast Cancer. Cancer Chemother Pharmacol 2001; 48:333-7.

Morais JAG, Wagner JG. A model describing the disposition of phenytoin in isolated rat hepatocytes. Biopharm Drug Dispos 1984; 5:357-76.