João Pedro Martins de Almeida Lopes

PhD (2001) in Chemical Engineering, Instituto Superior Técnico, Universidade técnica de Lisboa

Assistant Professor, Pharmaceutical Technology


Faculdade de Farmácia, Universidade de Lisboa — Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal

T (+351) 217 946 400
F (+351) 217946470
Researcher ID H-1733-2011
Group Researcher ID B-4826-2014
Scopus Author ID 7202733600

Research Interests

João Lopes current research interests are focused on the mathematical modelling aspects of solid dosage forms and nanoparticulate systems for modified drug delivery including manufacturing aspects focused on process analytical technology methodologies and incorporating concepts as QbD. He founded and coordinates since 2008 the research unit “Chemometrics and Process Analytical Technology” located at the FFUP. Multiple PAT-based systems for fast assessment of quality attributes of different products have been developed in partnership with industrial companies.

Selected Publications

Sarraguça MC, Lopes JA (2009) The use of net analyte signal (NAS) in NIR spectroscopy: interpretability and figures of merit, Anal. Chim. Acta, 642, 179-185 [doi:10.1016/j.aca.2008.10.006].

Sarraguça MC, De Beer T, Verdaet C, Remon J, Lopes JA (2010) A batch modelling approach to monitor a Ffreeze-drying process using in-line Raman spectroscopy, Talanta, 83(1), 130-138[doi:10.1016/j.talanta.2010.08.051].

Sousa CCS, Grosso F, Meirinhos-Soares L, Peixe L, Lopes JA (2014) Identification of carbapenem-resistant A. baumannii clones using infrared spectroscopy, J. Biophotonics, 7(5), 287–294 [doi: 10.1002/jbio.201200075].

Sarraguça MC, Ribeiro PR, Santos A, Silva MC, Lopes JA (2014) A PAT approach for the on-line monitoring of pharmaceutical co-crystals formation with near infrared spectroscopy, Int. J. Pharm., 471, 478-484 [doi:10.1016/j.ijpharm.2014.06.003].

Cruz MV, Sarraguça MC, Freitas F, Lopes JA, Reis MAM (2015) Online monitoring of P(3HB) produced from used cooking oil with near-infrared spectroscopy, J. Biotechnol., 194, 1-9 [doi: 10.1016/j.jbiotec.2014.11.022].