PhD (1991) in Pharmacy (Pharmaceutics), Universidade de Lisboa
Associate Professor with habilitation, Pharmaceutics
Faculdade de Farmácia, Universidade de Lisboa — Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal
Helena Marques leads the research group focussed on the development of non-parenteral drug delivery systems. Within this group, she uses a multidisciplinary approach to develop cyclodextrin based systems for pulmonary, transdermal, ophthalmic and oral delivery of bioactive molecules. Currently, she is focussed on the drug specific construction of cyclodextrin nanosystems able to modulate the desired physicochemical and pharmacokinetic profiles of loaded drug molecules in order to achieve its translocation across biological membranes for targeted delivery and pharmacologic activity.
Ascenso A, Pedrosa T, Pinho S, Pinho F, Oliveira JMF, Cabral Marques H, Oliveira H, Simões S, Santos C. The Effect of Lycopene Preexposure on UV-B-Irradiated Human Keratinocytes. Oxidative medicine and cellular longevity 2016; 8214631.
Salústio PJ, Cabral Marques HM, Costa PC, Pinto JF. Comparison of ibuprofen release from minitablets and capsules containing ibuprofen:β-cyclodextrin complex. Eur J Pharm Biopharm 2011; 78: 58-66.
Cabral Marques H, Almeida R. Optimisation of spray-drying variables for DPI formulation. Eur J Pharm Biopharm 2009; 73: 121–129.
Junco S, Casimiro T, Ribeiro N, Ponte MN, Cabral Marques H. A comparitive study of naproxen : b-cyclodextrin complexes prepared by conventional methods and using supercritical carbon dioxide. J Incl PhenomMacrocycl Chem 2002; 44: 117-121.
Cabral Marques HM, Hadgraf tJ, Kellaway IW, Taylor G. Studies of cyclodextrin inclusion complexes. Part IV. The pulmonary absorption of salbutamol from a complex with HP-b-cyclodextrin in rabbits. Int J Pharm 1991; 77: 303-307.