Cátia Ramalhete

PhD (2010) in Pharmacy (Pharmaceutical Chemistry), Universidade de Lisboa
Assistant professor, Universidade Atlântica

Faculdade de Farmácia, Universidade de Lisboa — Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal

T (+351) 217 946 400
F (+351) 217 946 470
Researcher ID M-8256-2013
Group Researcher ID B-5387-2014
Scopus Author ID 27067922700

Research Interests

C. Ramalhete interests are focused on the isolation, derivarization and structural characterization of bioactive compounds from African medicinal plants, with particular emphasis to those showing antimalarial activity. She is also involved in a recent project, coordinated by Prof. M.J. Ferreira, aiming the development of new P-gp modulators and antineoplastic agents, against MDR cancer cells.

Selected Publications

 

Ramalhete C, Mulhovo S, Molnar J, Ferreira MU. Triterpenoids from Momordica balsamina: Reversal of ABCB1-mediated multidrug resistance. Bioorg Med Chem. 2016; 24: 5061-5067.

Rocha E Silva LF, Ramalhete C, Nogueira KL, Mulhovo S, Ferreira MJ, Pohlit AM. In vivo evaluation of isolated triterpenes and semi-synthetic derivatives as antimalarial agents. Eur J Med Chem 2015; 18: 398-402.

Ramalhete C, da Cruz FP, Mulhovo S, Sousa IJ, Fernandes MX, Prudêncio M, Ferreira MJ. Dual-stage triterpenoids from an African medicinal plant targeting the malaria parasite. Bioorg Med Chem 2014; 22: 3887-3890

Ramalhete C, Magalhães LG, Rodrigues V, Mulhovo S, Da Silva Filho AA, Ferreira MJ. In vitro schistosomicidal activity of balsaminol F and karavilagenin C. Planta Medica 2012; 78: 1912-17.

Ramalhete C, da Cruz FP, Lopes D, Mulhovo S, Rosário VE, Prudêncio M, Ferreira MJ. Triterpenoids as inhibitors of erythrocytic and liver stages of Plasmodium infections. Bioorg Med Chem 2011; 19: 7474-81.

.