Bruno Miguel Nogueira Sepodes

PhD (2008) in Pharmacy (Pharmacology), Universidade de Lisboa
Assistant professor, Pharmacology and Pharmacotherapy

Faculdade de Farmácia, Universidade de Lisboa — Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal

T (+351) 217 946 400
F (+351) 217 946 470
Researcher ID A-4838-2014
Group Researcher ID B-5723-2014
Scopus Author ID 6507271629

Research Interests

Bruno’s research interests are in the field of critical care medicine, in particular, ischemia-reperfusion injury and multiple organ failure associated to systemic inflammation. His dynamic team focuses on the identification of new pharmacological targets and in the translation to the clinical setting. His other research and academic extension activities are in the field of rare diseases. Bruno is currently the Chair of the Committee of Orphan Medicinal Products and member of the Scientific Coordination Board of the European Medicines Agency.

Selected Publications

Vaquer G, Riviere F, Mavris M, Bignami F, Llinares-Garcia J, Westermark K, Sepodes B. Animal models for metabolic, neuromuscular and ophthalmological rare diseases. Nature Reviews Drug Discovery. 2013; 12:287-305

Maio R, Sepodes B, Patel NS, Thiemermann C, Mota-Filipe H, Costa P. Erythropoietin preserves the integrity and quality of organs for transplantation after cardiac death. Shock. 2011; 35:126-33

Amar Kapoor, Yasunori Shintani, Massimo Collino, Lucy K. Bailey, Nimesh S.A. Patel, Bruno Sepodes, Pinpat Tripatara, Sara Castiglia, Roberto Fantozzi, Helder Mota-Filipe, Ken Suzuki, Jane A. Mitchell, Christoph Thiemermann. Protective role of PPAR-β/δ in septic shock. American Journal of Respiratory and Critical Care Medicine. 2010; 182:1506-1515

Brines M, Patel NS, Villa P, Brines C, Mennini T, De Paola M, Erbayraktar Z, Erbayraktar S, Sepodes B, Thiemermann C, Ghezzi P, Yamin M, Hand CC, Xie QW, Coleman T, Cerami A. Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin. Proc Natl Acad Sci U S A. 2008; 105: 10925-30

Bruno Sepodes, Rui Maio, Rui Pinto, Edward Sharples, Muhammad Yaqoob, Michelle McDonald, Christoph Thiemermann, Helder Mota-Filipe. Recombinant human erythropoietin protects the liver from hepatic ischemia-reperfusion injury in the rat. Transplant International. 2006; 19: 919-26