Ana Francisca de Campos Simão Bettencourt

PhD (2006) in Pharmacy (Pharmaceutical Chemistry), Universidade de Lisboa
Assistant Professor, Toxicological and Bromatological Sciences

Faculdade de Farmácia, Universidade de Lisboa — Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal

T (+351) 217 946 400
F (+351) 217 946 470
Researcher ID M-4219-2013
Group Researcher ID B-4215-2014
Scopus Author ID 6603687672

Research Interests

Bettencourt major research interests are in the improvement of the therapeutic effects of local drug-delivery-systems for application in biomaterials-associated-infections (dental and orthopaedic). Specifically, novel strategies to overcome implant-associated infections are being developed mainly by the production and complete characterization (mechanical, physical and biological) of innovative polymeric local-drug delivery devices with controlled release properties and high anti-biofilm activity against multi-resistant pathogens.

Selected Publications

Martin V, Bettencourt A. Bone regeneration: Biomaterials as local delivery systems with improved osteoinductive properties. Mater Sci Eng C Mater Biol Appl; 2018; 82: 363-371.

Graça D, Louro H, Santos J, Dias K, Almeida AJ, Gonçalves L, Silva MJ, Bettencourt A. Toxicity screening of a novel poly(methylmethacrylate)-Eudragit nanocarrier on L929 fibroblasts. Toxicol Lett 2017; 276:129-137.

Santos-Ferreira I, Bettencourt A, Gonçalves LM, Kasper S, Bétrisey B, Kikhney J, Moter A, Trampuz A, Almeida AJ. Activity of Daptomycin and vVancomycin-loaded poly-epsilon-caprolactone microparticles against mature staphylococcal biofilms. Int J Nanomedicine 2015; 10:4351-66.

Matos A, Ribeiro I, Guedes R, Pinto R, Vaz M, Gonçalves L, Almeida AJ, Bettencourt A. Key-properties Outlook of a levofloxacin-loaded acrylic bone cement with improved antibiotic delivery. Int J Pharm 2015; 15; 485:317-28.

Bettencourt A, Calado A, Amaral J, Alfaia A, Vale FM, Monteiro J, Montemor MF, Ferreira MG, Castro M. Surface studies on acrylic bone cement. Int J Pharm 2004; 278: 181-6.